Calcium binding mode of γ-carboxyglutamic acids in conantokins
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چکیده
منابع مشابه
Calcium binding by bile acids: in vitro studies
In this study, we compared in vitro calcium binding by the taurine and glycine conjugates of the major bile acids in human bile: cholic (CA), chenodeoxycholic (CDCA) and deoxycholic (DCA) acids, together with the cholelitholytic bile acids unodeoxycholic (UDCA) and unocholic (UCA) acids. At physiological total calcium ( C a m ) (1-15 mM) and bile acid (BA) (10-50 mM) concentrations, all the bil...
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The calcium binding sites of Bakers' Yeast Transketolase (TK) was elucidated by estimating the pKa values of the functional groups that bind to calcium. These pKa's were found to be 6.25 and 7.2 relating to the pKa's of the two immidazol moieties of histidine residues on the enzyme. The rate of the binding of calcium to the enzyme was obtained separately as a function of pH. Maximum values ...
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The evolution of calcified tissues is a defining feature in vertebrate evolution. Investigating evolution of proteins involved in tissue calcification should help elucidate how calcified tissues have evolved. The purpose of this study was to collect and compare sequences of matrix and bone γ-carboxyglutamic acid proteins (MGP and BGP, respectively) to identify common features and determine the ...
متن کاملCompetition of zinc, cadmium and calcium for binding sites in sperm of trout and carp
Heavy metal pollutions of aquatic ecosystems have already raised many concerns on aquaticorganisms’health and survival especially on their sperm. The effects of a single metal on sperm may be totallydifferent from cocktail of several metals because of their interactions, so the effects of zinc, cadmium andcalcium on the trout and carp sperms and their competition have been examined by incubatio...
متن کاملCalcium binding by bile acids: in vitro studies using a calcium ion electrode.
In this study, we compared in vitro calcium binding by the taurine and glycine conjugates of the major bile acids in human bile: cholic (CA), chenodeoxycholic (CDCA) and deoxycholic (DCA) acids, together with the cholelitholytic bile acids ursodeoxycholic (UDCA) and ursocholic (UCA) acids. At physiological total calcium (CaTOT) (1-15 mM) and bile acid (BA) (10-50 mM) concentrations, all the bil...
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ژورنال
عنوان ژورنال: Protein Engineering, Design and Selection
سال: 1999
ISSN: 1741-0134,1741-0126
DOI: 10.1093/protein/12.7.589